La Periquera is one of the most well-known historical buildings in the city of Holguín. It is located across from Calixto García Park, formerly the Plaza de Armas, in the city center.

Mirador de Mayabe (Mayabe lookout), located in the province of Holguín, is an emblematic place that combines nature and culture.

In front of the La Periquera Provincial Museum, the people of Holguín paid posthumous tribute to the 32 Cuban combatants who fell during the U.S. attack on the Bolivarian Republic of Venezuela. With profound sorrow, Cuba mourned its sons, while at the same time trembling with pride in knowing them to be worthy, to never waver or betray history, and to defend just causes, peace, and the sovereignty of the Americas.

The Polinesio Restaurant in Holguín, the second of its kind in Cuba, located atop the Sierra Cristal building (known as the 12-story building) in this eastern city, reopened its doors to the public on December 30, 2025.